DEFORMATION BEHAVIOUR OF GELLAN GUM BASED ARTIFICIAL BONE STRUCTURES UNDER SIMULATED PHYSIOLOGICAL CONDITIONS

Authors

  • Nela Krčmářová Czech Technical University in Prague, Faculty of Transportation Sciences, Department of Mechanics and Materials, Konviktská 20, 120 00 Prague 1, Czech Republic
  • Jan Šleichrt Czech Technical University in Prague, Faculty of Transportation Sciences, Department of Mechanics and Materials, Konviktská 20, 120 00 Prague 1, Czech Republic
  • Tomáš Fíla Institute of Theoretical and Applied Mechanics AS CR, v.v.i., Prosecká 76, 190 00 Prague 9, Czech Republic
  • Petr Koudelka Institute of Theoretical and Applied Mechanics AS CR, v.v.i., Prosecká 76, 190 00 Prague 9, Czech Republic
  • Daniel Kytýř Institute of Theoretical and Applied Mechanics AS CR, v.v.i., Prosecká 76, 190 00 Prague 9, Czech Republic

DOI:

https://doi.org/10.14311/APP.2017.7.0029

Abstract

The paper deals with investigation of deformation behaviour of gellan gum (GG) based structures prepared for regenerative medicine purposes. Investigated material was synthesized as porous spongy-like scaffold reinforced by bioactive glass (BAG) nano-particles in different concentrations. Deformation behavior was obtained employing custom designed experimental setup. This device equipped with bioreactor chamber allows to test the delivered samples under simulated physiological conditions with controlled flow and temperature. Cylindrical samples were subjected to uniaxial quasistatic loading in tension and compression. Material properties of plain GG scaffold and reinforced scaffold buffered by 50wt% and 70wt% BAG were derived from a set of tensile and compression tests. The results are represented in form of stress-strain curves calculated from the acquired force and displacement data.

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Published

2016-12-09

Issue

Vol. 7 (2017): ExNum 2016

Section

Articles

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